the precise solution by sfm
Successful reconstitution of lyophilized medications depends crucially on the properties of the active substance as well as the solvent. That's why transfer systems are available with parameters that can be individually adapted. The nextaro® premium transfer system can be tailored to your specific requirements.
Protein-based medications (such as coagulation factors) can be stored more safely and last longer with freeze-drying (lyophilization). Modern transfer systems make reactivation of lyophilized substances easy and reliable for the user. Transfer systems need to be easily adaptable to the specific requirements of the application because the physical properties of the active substances and the solvents can differ.
The solubility of the active substance as well as the volume and viscosity of the solvent are decisive for successful reconstitution of lyophilized medications. The angle and force with which the jet of liquid hits the lyophilized cake are particularly important. If the jet is too strong, foam may form and cause denaturation or clumping of the active substance. Ideally, the jet of solvent is directed gently down the walls of the vial in order to dissolve the active substance slowly from below. Adjustment of the transfer rate is therefore essential for complete reconstitution and standardized concentration of the active substance in the prepared solvent.
To maintain a regulated transfer speed of the solution when reconstituting a lyophilized medication, the nextaro® premium transfer system contains an integrated throttle, which can be implemented to match your individual requirements. This ensures that, through customizing and specifying the internal geometry and thus the flow characteristics, the liquid jet will be adapted specifically to the solvent volume and the solubility of the active substance. This gentle form of reconstitution prevents foaming, clumping and denaturation.
At sfm medical devices GmbH, we help you to develop a reliable reconstitution kit for your customers that is safe, robust and intuitive to use, and is suitable for the clinic as well as the home care sector. We will find the right parameters for your application of the nextaro® premium transfer system. To do this, we carry out individual tests and adjust the nextaro® premium transfer system to the properties of your specific components. The result is an optimized overall concept that can be implemented as a standard product.
How can a mixing and transfer device offer users more benefits and enhance usability through optimized user-friendliness? These were the questions we thoroughly considered when embarking on the development of the nextaro® product family.
The nextaro® product family continues to grow steadily. The new developments are oriented towards the wishes and needs of the market. The focus of the product family lies in the highest quality solutions for the user and patient.
We are pleased to announce that our innovative medical product nextaro® has been successfully approved in Canada. This further milestone represents an important step in our international expansion and confirms the quality and recognition of our product.
Medical device approval in Canada requires thorough review and compliance with strict regulatory requirements. Our team worked closely with Canadian health authorities to submit all required…
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nextaro® is manufactured and distributed by:
sfm medical devices GmbH, Brückenstraße 5, 63607 Wächtersbach (Germany)
